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SS-31 (Elamipretide) Peptide (50mg)

$114.00

SS-31 (Elamipretide) peptide — a COA-verified mitochondria-targeted peptide studied in laboratory research for its interaction with inner mitochondrial membrane signaling and bioenergetic regulatory pathways. Supplied as a high-purity, research-only peptide for investigational use.

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Overview

SS-31, also known as Elamipretide, is a synthetic tetrapeptide designed to selectively localize to the inner mitochondrial membrane. In laboratory research settings, SS-31 has been studied for its ability to interact with mitochondrial phospholipids and influence signaling pathways associated with mitochondrial structure and function.

This compound is supplied strictly for laboratory and investigational research purposes.


Compound Breakdown

Unlike systemically acting metabolic peptides, SS-31 targets mitochondrial membranes directly. In preclinical research models, SS-31 has been investigated for its role in:

  • Inner mitochondrial membrane stabilization

  • Cardiolipin-associated signaling pathways

  • Mitochondrial bioenergetic regulation mechanisms

  • Reactive oxygen species–associated signaling modulation

Its membrane-targeted profile makes SS-31 a valuable research tool for studying mitochondrial-specific signaling processes.


Research Context

Research investigations involving SS-31 commonly explore:

  • Mitochondrial signaling and bioenergetics models

  • Cellular stress response at the mitochondrial level

  • Comparative studies alongside mitochondrial-derived peptides

  • Integrated metabolic research frameworks involving mitochondrial regulation

These investigations remain limited to controlled laboratory environments and do not imply clinical or therapeutic outcomes.


Related Categories

SS-31 is frequently studied alongside MOTS-c Peptide and incorporated into advanced metabolic research formulations such as the SS-31 + MOTS-c Bundle.

Testing & Verification

Each batch supplied by Not Labs undergoes independent analytical testing to verify compound identity, purity, and integrity. Batch-specific Certificates of Analysis (COAs) are provided for transparency and research verification purposes.

Where applicable, purity specifications (≥99%) are indicated on product labeling and corresponding COA documentation.

SS-31 (Elamipretide) peptide vial 50mg for laboratory research use

Research FAQ

1. What makes SS-31 different from other metabolic research peptides?
SS-31 is designed to localize directly to the inner mitochondrial membrane, allowing investigation of mitochondrial-specific signaling pathways rather than systemic metabolic signaling.

2. What research areas commonly utilize SS-31?
Laboratory research includes mitochondrial bioenergetics studies, membrane signaling investigations, and cellular stress response models.

3. How does SS-31 relate to MOTS-c in research settings?
SS-31 and MOTS-c are often studied together to examine complementary aspects of mitochondrial signaling and metabolic regulation.

4. How should SS-31 be stored for laboratory research?
Lyophilized SS-31 is typically stored at −20 °C. After reconstitution, aliquoting and refrigerated storage are commonly used to support experimental stability.

Scientific References

References:

  1. Mitchell W, Ng EA, Tamucci JD, et al. The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanism of action. Journal of Biological Chemistry.
    https://pubmed.ncbi.nlm.nih.gov/32273339/

  2. Chavez JD, Tang X, Campbell MD, et al. Mitochondrial protein interaction landscape of SS-31. Proceedings of the National Academy of Sciences of the United States of America.
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7334473/

  3. Campbell MD, Duan J, Samuelson AT, et al. Improving mitochondrial function with SS-31 reverses age-related redox stress and improves exercise tolerance in aged mice. Free Radical Biology and Medicine.
    https://pmc.ncbi.nlm.nih.gov/articles/PMC6588449/

  4. Chiao YA, Zhang H, Sweetwyne M, et al. Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice. eLife.
    https://elifesciences.org/articles/55513

  5. Daubert MA, Yow E, Dunn G, et al. Novel Mitochondria-Targeting Peptide in Heart Failure Treatment: A Randomized, Placebo-Controlled Trial of Elamipretide. Circulation: Heart Failure.
    https://pubmed.ncbi.nlm.nih.gov/29217757/

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