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CJC-1295 (DAC) Peptide (5mg)

$56.00

CJC-1295 (DAC) peptide — a COA-verified growth hormone–releasing hormone (GHRH) analog modified with a Drug Affinity Complex (DAC) to extend plasma half-life in laboratory research models. Supplied as a high-purity, research-only peptide for investigational use.

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COA Available Batch Documented HPLC Verified

Overview

CJC-1295 (DAC) is a synthetic peptide analog of growth hormone–releasing hormone (GHRH) that incorporates a Drug Affinity Complex (DAC) designed to bind circulating serum proteins. This modification significantly prolongs peptide persistence in preclinical research models, allowing sustained receptor engagement over extended timeframes.

This compound is supplied strictly for laboratory and investigational research purposes.


Compound Breakdown

The Drug Affinity Complex (DAC) component enables CJC-1295 to reversibly associate with albumin, reducing rapid clearance observed with non-modified GHRH analogs. In laboratory research settings, this allows investigation into:

  • Prolonged GHRH receptor stimulation

  • Sustained growth hormone signaling dynamics

  • Temporal signaling effects associated with extended peptide exposure

  • Comparative duration-dependent pathway activation

This extended activity profile distinguishes CJC-1295 (DAC) from shorter-acting GHRH analogs.


Research Context

Research investigations involving CJC-1295 (DAC) commonly explore:

  • Long-duration growth hormone signaling models

  • Endocrine rhythm and signaling persistence studies

  • Comparative research versus non-DAC GHRH analogs

  • Experimental frameworks requiring reduced dosing frequency

These studies are limited to controlled laboratory environments and do not imply clinical or therapeutic outcomes.


Related Categories

CJC-1295 (DAC) is frequently compared with CJC-1295 (No DAC) Peptide and is also incorporated into combination research formulations such as the GH Release Bundle.

Testing & Verification

Each batch supplied by Not Labs undergoes independent analytical testing to verify compound identity, purity, and integrity. Batch-specific Certificates of Analysis (COAs) are provided for transparency and research verification purposes.

Where applicable, purity specifications (≥99%) are indicated on product labeling and corresponding COA documentation.

CJC-1295 DAC COA certificate of analysis for research compound purity

Research FAQ

1. What does “DAC” mean in CJC-1295 (DAC)?
DAC refers to a Drug Affinity Complex that allows the peptide to reversibly bind serum proteins, extending its persistence in research models.

2. How does CJC-1295 (DAC) differ from CJC-1295 (No DAC)?
CJC-1295 (DAC) is designed for prolonged signaling studies, whereas CJC-1295 (No DAC) is typically examined in shorter-duration research frameworks.

3. Why do researchers choose the DAC version?
The DAC modification enables investigation of sustained receptor engagement and long-term signaling effects without rapid peptide clearance.

4. How should CJC-1295 (DAC) be stored for laboratory research?
Lyophilized CJC-1295 (DAC) is typically stored at −20 °C. After reconstitution, aliquoting and refrigerated storage are commonly used to support experimental stability.

Scientific References

  1. Jetté L, Léger R, Thibaudeau K, et al. Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog. Endocrinology.
    https://pubmed.ncbi.nlm.nih.gov/15817669/

  2. Alba M, Fintini D, Sagazio A, et al. Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse. American Journal of Physiology-Endocrinology and Metabolism.
    https://pubmed.ncbi.nlm.nih.gov/16822960/

  3. Ionescu M, Frohman LA. Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. The Journal of Clinical Endocrinology & Metabolism.
    https://pubmed.ncbi.nlm.nih.gov/17018654/

  4. Timms M, Ganio K, Steel R. A method for confirming CJC-1295 abuse in equine plasma samples by LC-MS/MS. Drug Testing and Analysis.
    https://pubmed.ncbi.nlm.nih.gov/30938069/

  5. Memdouh S, Thomas A, McCullough B, et al. Advances in the detection of growth hormone releasing hormone synthetic analogs. Drug Testing and Analysis.
    https://pubmed.ncbi.nlm.nih.gov/34665524/

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