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IGF-1 LR3 Peptide (0.1mg / 1mg)

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IGF-1 LR3 peptide in 0.1mg and 1mg vials. Investigated for muscle growth, glucose metabolism, and cellular proliferation in research models. COA-verified.

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Overview

IGF-1 LR3 peptide (Insulin-like Growth Factor 1 Long R3) is a modified version of human IGF-1 with an extended half-life. Through substitution of arginine for glutamic acid at position 3 and a 13-amino acid N-terminal extension, IGF-1 LR3 demonstrates increased stability and reduced binding to IGF-binding proteins. This makes it a powerful research tool for studying muscle growth, glucose regulation, and cell proliferation in preclinical models.

Compound Breakdown

  • IGF-1 LR3 (0.1mg / 1mg): Modified insulin-like growth factor analog with extended half-life. Investigated for cellular proliferation, muscle repair, and glucose metabolism studies.

Research Applications

Preclinical research with IGF-1 LR3 peptide has explored:

  • Muscle Growth and Repair → studied for satellite cell activation, protein synthesis, and hypertrophy models.

  • Cellular Proliferation → investigated for tissue regeneration and repair processes.

  • Glucose Regulation → studied for insulin-like effects on glucose uptake and metabolism.

  • Neuroprotection → explored for potential influence on neuronal survival and repair.

  • Comparative Studies → evaluated against native IGF-1 for stability, receptor affinity, and bioavailability in research models.

Related Categories

IGF-1 LR3 is part of the Muscle & Physique category. It is sometimes studied alongside Tesamorelin and Ipamorelin in anabolic and metabolic research models.

Compliance Statement

All Not Labs products are strictly for research use only and are not intended for human or veterinary use.

Certificate of Analysis

FAQ

What is IGF-1 LR3 peptide studied for in research?
IGF-1 LR3 is investigated for muscle growth, glucose metabolism, and cellular proliferation in preclinical studies.

How does IGF-1 LR3 differ from native IGF-1?
IGF-1 LR3 has an arginine substitution at position 3 and an extended N-terminal sequence, reducing binding to IGF-binding proteins and extending half-life.

What biological processes are linked to IGF-1 LR3 peptide?
Research connects IGF-1 LR3 to muscle hypertrophy, glucose regulation, tissue regeneration, and neuronal survival.

Which research models are used for IGF-1 LR3 studies?
Models include skeletal muscle growth, glucose tolerance, wound healing, and neuroprotection.

How is IGF-1 LR3 peptide quality verified?
Every batch is supported by a Certificate of Analysis (COA) confirming purity and molecular identity.

References

References:

  1. Tomas FM, Lemmey AB, Read LC, Ballard FJ. (1996). Superior potency of IGF-I analogues that bind poorly to binding proteins, including LR3 IGF-I. Journal of Endocrinology. PubMed
  2. Tomas FM. (2001). LR3IGF-I ameliorates body weight loss in food-restricted rats. Growth Hormone & IGF Research. PubMed
  3. Cell Sciences. (2015). Quantitation of LONG®R3 IGF-I during production confirms extended half-life compared to IGF-1. Technical Whitepaper. Cell Sciences

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