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MOTS-c Peptide (10mg / 40mg)

Price range: $64.00 through $154.00

MOTS-c peptide — a COA-verified mitochondrial-derived peptide studied in laboratory research for its role in cellular metabolism, mitochondrial signaling, and metabolic regulation pathways. Supplied as a high-purity, research-only peptide for investigational use.

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COA Available Batch Documented HPLC Verified

Overview

MOTS-c is a mitochondrial-derived peptide encoded within the mitochondrial genome and expressed in response to cellular metabolic stress. In laboratory research settings, MOTS-c has been studied for its involvement in metabolic signaling pathways that coordinate mitochondrial function with nuclear gene expression.

This compound is supplied strictly for laboratory and investigational research purposes.

Compound Breakdown

Unlike nuclear-encoded peptides, MOTS-c originates from mitochondrial DNA, positioning it as a unique signaling molecule in metabolic regulation research. In preclinical models, MOTS-c has been investigated for its influence on:

  • Mitochondrial–nuclear communication pathways

  • Cellular metabolic adaptation mechanisms

  • Glucose and lipid metabolism–associated signaling

  • Stress-responsive metabolic regulation frameworks

Its mitochondrial origin makes MOTS-c a distinct tool for studying intracellular metabolic coordination.

Research Context

Research investigations involving MOTS-c commonly explore:

  • Metabolic flexibility and cellular adaptation models

  • Mitochondrial signaling responses to metabolic stress

  • Comparative studies alongside incretin-based research compounds

  • Combination research frameworks targeting systemic metabolic regulation

These investigations remain limited to controlled laboratory environments and do not imply clinical or therapeutic outcomes.

Related Categories

MOTS-c is frequently studied alongside Semaglutide Peptide, Tirzepatide Peptide, and Retatrutide Peptide, and is also incorporated into metabolic research formulations such as the Metabolic Bundle I: Classic, Metabolic Bundle II: Synergy, and Metabolic Bundle III: Next Gen.

Testing & Verification

Each batch supplied by Not Labs undergoes independent analytical testing to verify compound identity, purity, and integrity. Batch-specific Certificates of Analysis (COAs) are provided for transparency and research verification purposes.

Where applicable, purity specifications (≥99%) are indicated on product labeling and corresponding COA documentation.

MOTS-c COA – Mitochondrial Peptide Research Certificate | Not Labs

Research FAQ

1. What makes MOTS-c different from other metabolic research peptides?
MOTS-c is derived from mitochondrial DNA rather than nuclear DNA, allowing researchers to study mitochondrial-specific signaling pathways involved in metabolic regulation.

2. Why is MOTS-c often studied alongside incretin-based compounds?
Research frameworks frequently examine mitochondrial signaling and incretin pathways together to better understand coordinated metabolic regulation.

3. What research areas commonly utilize MOTS-c?
Laboratory research includes metabolic regulation models, mitochondrial signaling studies, and investigations into cellular adaptation to metabolic stress.

4. How should MOTS-c be stored for laboratory research?
Lyophilized MOTS-c is typically stored at −20 °C. After reconstitution, aliquoting and refrigerated storage are commonly used to support experimental stability.

Scientific References

References:

  1. Reynolds JC, et al. (2021). Mitochondrial-encoded MOTS-c is an exercise-induced regulator of physical performance. Nature Communications. Nature Communications
  2. Wan W, et al. (2023). Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging. Journal of Translational Medicine. J Transl Med
  3. Kumagai H, et al. (2021). MOTS-c reduces myostatin and muscle atrophy signaling in high-fat diet mice. American Journal of Physiology – Endocrinology & Metabolism. AJP Endocrinology & Metabolism

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