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Retatrutide Peptide (15mg / 30mg)

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Retatrutide peptide in a 10mg vial. Investigated as a GLP-1, GIP, and glucagon receptor agonist for metabolic and weight regulation research. COA-verified.

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Overview

Retatrutide peptide is a novel multi-receptor agonist studied for its unique ability to activate the GLP-1, GIP, and glucagon receptors simultaneously. This triple agonist profile distinguishes it from earlier incretin-based peptides, allowing for broader investigation of metabolic regulation, energy expenditure, and body weight management. Preclinical studies suggest Retatrutide peptide influences glucose balance, lipid metabolism, and satiety pathways, making it a promising tool in metabolic and obesity-related research.

Compound Breakdown

  • Retatrutide (10mg): Synthetic peptide agonist targeting GLP-1, GIP, and glucagon receptors. Studied for glucose metabolism, body weight regulation, and multi-pathway metabolic research.

Research Applications

Preclinical investigations into Retatrutide peptide include:

  • Glucose Regulation → studied for improving insulin sensitivity and lowering blood glucose.

  • Weight Regulation → examined for effects on energy balance, satiety, and body composition.

  • Lipid Metabolism → investigated for impact on cholesterol, fatty acid oxidation, and triglyceride regulation.

  • Multi-Pathway Metabolic Research → explored for simultaneous activation of GLP-1, GIP, and glucagon receptors.

  • Comparative Models → studied against single and dual incretin agonists to evaluate enhanced efficacy in metabolic regulation.

Related Categories

Retatrutide is part of the Metabolic category. It is often compared with Tirzepatide and Semaglutide in incretin pathway and weight regulation research.

Compliance Statement

All Not Labs products are strictly for research use only and are not intended for human or veterinary use.

Certificate of Analysis

FAQ

What is Retatrutide peptide studied for in research?
Retatrutide is studied as a GLP-1, GIP, and glucagon receptor agonist for its impact on glucose metabolism, weight regulation, and energy expenditure.

How does Retatrutide differ from other incretin-based peptides?
Unlike single or dual incretin agonists, Retatrutide simultaneously activates GLP-1, GIP, and glucagon receptors, offering a broader research profile.

Which biological processes are linked to Retatrutide peptide?
Research suggests Retatrutide influences glucose balance, lipid metabolism, satiety signaling, and body composition.

What research models are commonly used with Retatrutide?
Rodent models of obesity, insulin resistance, and glucose intolerance are common preclinical applications.

Can Retatrutide peptide be studied alongside other metabolic peptides?
Yes. It is often compared with or studied in combination with Semaglutide, Tirzepatide, and other incretin agonists.

How is Retatrutide peptide quality assured?
Every batch is COA-verified, confirming molecular identity and purity.

References

References:

  1. Sanyal AJ, et al. (2024). Retatrutide is a novel triple agonist of the glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1 and glucagon receptors. Nature Medicine. Nature Medicine
  2. Jastreboff AM, et al. (2023). Triple-Hormone-Receptor Agonist Retatrutide for Obesity. New England Journal of Medicine. NEJM
  3. Urva S, et al. (2023). Retatrutide (LY3437943) is a novel GIP/GLP-1/glucagon receptor agonist under investigation for chronic weight management and its complications. Diabetes, Obesity and Metabolism. Diabetes, Obesity and Metabolism
  4. Katsi V, et al. (2025). Retatrutide — A Game Changer in Obesity Pharmacotherapy. Biomolecules. Biomolecules (MDPI)

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