Overview
GH Release Bundle peptides are a dual-compound research set that bring together CJC-1295 (No DAC) and Ipamorelin — two well-studied secretagogues known for their complementary actions on the growth hormone (GH) axis. By combining a GHRH analog with a selective ghrelin receptor agonist, this bundle provides a robust model for studying pulsatile GH release, IGF-1 signaling, and endocrine adaptation. Researchers use the GH Release Bundle to explore hormonal regulation, tissue repair, and comparative outcomes between single-agent and combined administration.
Compound Breakdown
CJC-1295 (No DAC, 5mg) → A synthetic analog of growth hormone–releasing hormone (GHRH). CJC-1295 has been studied for its ability to stimulate GH secretion and elevate IGF-1 levels in preclinical models, with research highlighting its role in prolonged GH pulsatility.
Ipamorelin (5mg) → A selective ghrelin mimetic that binds specifically to the ghrelin receptor (GHS-R1a). Ipamorelin has been investigated for its GH-releasing activity without significantly impacting cortisol or prolactin, making it an attractive model for selective endocrine stimulation.
Research Context
GH Release Bundle peptides combine CJC-1295’s GHRH pathway activation with Ipamorelin’s ghrelin receptor stimulation, producing synergistic GH release in controlled settings. This dual mechanism enables researchers to investigate:
Pituitary signaling and feedback regulation.
Comparative GH secretion versus single-compound studies.
Downstream IGF-1 activity and metabolic endpoints.
The bundle also allows for the exploration of pulsatile GH release, receptor-specific signaling pathways, and potential overlap with metabolic and recovery models.
Applications
Research areas supported by the GH Release Bundle include:
Growth Hormone Secretion Studies → Evaluating combined GHRH and ghrelin receptor stimulation for enhanced GH pulsatility.
Endocrine Pathway Research → Studying pituitary response, receptor binding, and GH axis regulation.
Comparative Studies → Assessing the difference between dual-compound administration and single-compound models.
Muscle & Physique Research → Investigating GH/IGF-1 signaling related to muscle recovery, growth, and body composition.
Longevity & Metabolic Models → Exploring GH axis effects on metabolism, energy regulation, and biomarkers of aging.
Related Categories
The GH Release Bundle is part of our Bundles – Best Value collection. It also belongs to the Hormone Compounds category, featuring CJC-1295 No DAC and Ipamorelin.
Compliance Statement
All Not Labs products are intended strictly for laboratory research use only. The GH Release Bundle is not approved for human or veterinary use.
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