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5-Amino-1MQ Peptide (50mg)

$79.00

5-Amino-1MQ peptide — a COA-verified research compound studied for its role in nicotinamide metabolism, NNMT inhibition pathways, and cellular energy regulation. Supplied as a high-purity, research-only material for laboratory investigation.

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COA Available Batch Documented HPLC Verified

Overview

5-Amino-1MQ is a small-molecule research compound investigated for its interaction with nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular methylation balance and metabolic regulation. In laboratory research settings, 5-Amino-1MQ has been used to explore pathways related to cellular energy utilization, adipocyte metabolism, and nicotinamide signaling dynamics.

This compound is supplied strictly for investigational and laboratory research purposes.


Compound Breakdown & Research Context

NNMT plays a role in regulating intracellular nicotinamide availability, influencing downstream NAD⁺-dependent processes in preclinical models. By inhibiting NNMT activity, 5-Amino-1MQ has been studied as a research tool for examining:

  • Nicotinamide and methyl donor balance

  • Cellular energy homeostasis pathways

  • Metabolic signaling associated with adipose tissue models

  • Regulatory mechanisms affecting NAD⁺-linked enzymatic systems

These investigations remain limited to controlled laboratory environments and do not imply clinical outcomes.


Related Categories

5-Amino-1MQ is commonly studied alongside NAD⁺ Peptide and MOTS-c Peptide in metabolic and cellular energy research models.

Testing & Verification

Each batch supplied by Not Labs undergoes independent analytical testing to verify compound identity, purity, and integrity. Batch-specific Certificates of Analysis (COAs) are provided for transparency and research verification purposes.

Where applicable, purity specifications (≥99%) are indicated on product labeling and corresponding COA documentation.

5-Amino-1MQ COA certificate of analysis for research compound purity

Research FAQ

1. What distinguishes 5-Amino-1MQ from direct NAD⁺ supplementation compounds?
5-Amino-1MQ is studied for its interaction with NNMT-mediated pathways rather than direct NAD⁺ provision, allowing researchers to investigate upstream regulatory mechanisms affecting nicotinamide metabolism.

2. What research areas commonly utilize 5-Amino-1MQ?
Preclinical research has explored applications related to metabolic regulation, adipocyte signaling, and cellular energy balance in controlled laboratory models.

3. Is 5-Amino-1MQ considered a peptide?
Although frequently grouped with peptide research compounds, 5-Amino-1MQ is a small-molecule NNMT inhibitor and is classified accordingly for research use.

4. How should 5-Amino-1MQ be handled in laboratory settings?
Handling and storage should follow standard laboratory protocols appropriate for small-molecule research compounds, as outlined in batch-specific documentation.

Scientific References

  1. Babula JAJ, et al. Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction. Diabetes Obes Metab.
    https://pubmed.ncbi.nlm.nih.gov/39161060/

  2. Dimet-Wiley A, et al. Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice. Sci Rep.
    https://pubmed.ncbi.nlm.nih.gov/35013352/

  3. Akar S, et al. Small molecule inhibitor of nicotinamide N-methyltransferase shows anti-proliferative activity in HeLa cells. J Enzyme Inhib Med Chem.
    https://pubmed.ncbi.nlm.nih.gov/33645410/

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